4-(2-Thienoyl)butyric acid

4-(2-Thienoyl)butyric acid - Names and Identifiers

Name	4-(2-Thienoyl)butyric acid
Synonyms	4-(2-Thienoyl)butyric acid 5-(2-THIENOYL)BUTYRIC ACID 4-(2-THIENOYL)BUTYRIC ACID 5-oxo-5-(2-thienyl)valeric acid 5-OXO-5-(2-THIENYL)VALERIC ACID 5-keto-5-(2-thienyl)valeric acid 2-Thiophenepentanoic acid, δ-oxo- 5-oxo-5-(thiophen-2-yl)pentanoic acid N'-[4-(hydroxymethyl)-2,5-diphenyl-3-pyrazolyl]-N,N-dimethylmethanimidamide
CAS	22971-62-6
InChI	InChI=1/C9H10O3S/c10-7(3-1-5-9(11)12)8-4-2-6-13-8/h2,4,6H,1,3,5H2,(H,11,12)

4-(2-Thienoyl)butyric acid - Physico-chemical Properties

Molecular Formula	C9H10O3S
Molar Mass	198.24
Density	1.282±0.06 g/cm3(Predicted)
Melting Point	94-97°C
Boling Point	407.8±25.0 °C(Predicted)
Flash Point	200.5°C
Vapor Presure	2.2E-07mmHg at 25°C
BRN	141775
pKa	4.59±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.561
MDL	MFCD00151848

4-(2-Thienoyl)butyric acid - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29349990

4-(2-Thienoyl)butyric acid - Introduction

4-(2-Thienoyl)butyric acid, also known as 4-(2-thienyl) butyric acid, is an organic compound. Its chemical formula is C9H8O3S and its molecular weight is 196.23g/mol. The following is a description of the properties, uses, preparation methods and safety information of the compound:

Nature:
-Appearance: 4-(2-Thienoyl)butyric acid is a white solid.
-Solubility: It is soluble in common organic solvents, such as ethanol and dimethyl sulfoxide.
-Melting point: approximately 116-119 ° C.
-Stability: It is relatively stable under normal temperature and pressure.

Use:
- 4-(2-Thienoyl)butyric acid is a compound with potential medicinal value and has a variety of biological activities. It is studied for anti-tumor, anti-inflammatory, anti-oxidation and other fields.
-It can also be used as an important intermediate in organic synthesis.

Method:
- 4-(2-Thienoyl)butyric acid can be prepared by the reaction of 2-thiophenone and bromoacetic anhydride. First, 2-thiopheneethyl ketone is reacted with iodoacetic acid under basic conditions to obtain a bromo derivative of 2-thiopheneethyl ketone. The resulting bromo derivative is then reacted with sodium butyrate under basic conditions to give the target product.

Safety Information:
- 4-(2-Thienoyl)butyric acid has limited safety-related information, and no specific safety-related issues have been identified in the available information. However, when handling any chemical substance, always follow the correct laboratory safety regulations and operating procedures, and operate according to the recommendations of the Material Safety Data Sheet (MSDS). If an accident occurs, medical advice should be sought immediately.

Last Update：2024-04-10 22:29:15